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Hannah Went: Cofounder of TruDiagnostic

Feb 63 min read

Updated: 3 days ago

Episode 54: Want to Know How Fast Your Body Is Aging? Biological Age Testing Is the New Olympics of Longevity – Learn How to Test Your Biological Age and the Key Factors That Influence Aging with Hannah Went, Co-Founder of TruDiagnostic




Episode Highlights:


In this episode of the BiohackerBlondie Podcast, Jenny sits down with Hannah Went, co-founder of True Diagnostic, to dive deep into epigenetics, biological age testing, and the latest advancements in longevity science. Hannah shares how biological age is measured, what lifestyle factors impact it the most, and how True Diagnostic is leading the way in research-backed epigenetic testing.


Key Topics Discussed:


Understanding Biological vs. Chronological Age


  • Chronological Age: The number of years you’ve been alive.

  • Biological Age: How old your body is on a cellular level, influenced by lifestyle and environment.

  • Why some people "age better" than others and how biological age testing helps measure this.


How True Diagnostic Measures Aging


  • Uses epigenetic DNA methylation to determine biological age.

  • Tests over a million markers to see which genes are turned on/off.

  • More predictive than telomere length, grip strength, or lab-based biological age tests.


Key Lifestyle Factors That Impact Biological Age


Hannah highlights four major lifestyle factors that significantly influence aging:


  • Stress Management – Chronic stress accelerates biological aging.

  • Sleep Optimization – Quality sleep supports cellular repair and longevity.

  • Diet & Nutrition – What you eat plays a major role in gene expression.

  • Physical Activity & Exercise – Staying active slows aging on a cellular level.


Caloric Restriction & Aging


  • One of the most researched anti-aging interventions.

  • Even small reductions in caloric intake may help slow biological aging.

  • Eating nutrient-dense whole foods instead of just focusing on calorie restriction.


Diet & Biological Age – The Vegan vs. Omnivore Study


  • True Diagnostic partnered with Stanford University to study the effects of a vegan vs. omnivore diet on aging.

  • Results: Vegans aged slightly slower over 8 weeks, but long-term deficiencies could occur without careful planning.

  • Key takeaway: Diet quality matters more than labels – prioritize nutrient-dense foods.


True Diagnostic vs. Other Biological Age Tests


  • GlycanAge – Focuses on immune function & inflammation markers.

  • Function Health – Uses blood biomarkers, not DNA methylation.

  • True Diagnostic – Measures epigenetic markers with the most predictive algorithms.


Can Ozempic & Weight Loss Drugs Reduce Biological Age?


  • True Diagnostic is currently studying Ozempic & GLP-1 drugs with Cornell University.

  • Preliminary findings suggest improved insulin sensitivity & reduced inflammation may contribute to a lower biological age.


The Rejuvenation Olympics & Measuring Longevity


  • The Rejuvenation Olympics ranks participants by how well they slow aging.

  • True Diagnostic is the primary test used.

  • Hannah explains why aging speed matters more than just lowering biological age.


Best Supplements for Slowing Biological Aging


Hannah shares key longevity-supporting nutrients backed by research:


  • Vitamin C – Powerful antioxidant

  • Vitamin D – Essential for immune function

  • Creatine – Supports muscle function & brain health

  • Magnesium – Helps with relaxation & cellular health

  • B Vitamins – Crucial for energy metabolism & methylation

  • Alpha-Ketoglutarate (AKG) – Supports cellular repair

  • NAD Precursors (NR/NMN) – Helps maintain energy levels


Hormones & Aging – Menopause, Pregnancy, & Biological Age


  • Menopause speeds up biological aging – Estrogen therapy may help slow it.

  • Pregnancy temporarily increases biological age but reverses postpartum.

  • Chronic stress, inflammation, and toxins can impact aging speed.


Peptides & Longevity – Do They Work?


  • Peptides like Thymosin Alpha-1 & Thymosin Beta-4 may support immune function.

  • Mitochondrial peptides (SS-31, MOTS-c) could enhance energy & longevity.

  • FDA regulations make peptide research challenging, so long-term effects are still being explored.


True Diagnostic’s At-Home Tests


  • TrueAge Test: Measures biological age, pace of aging, and lifestyle factors.

  • TrueHealth Test: Tracks vitamins, minerals, toxins, and NAD metabolism.

  • Combo Test: Get both tests together for a full longevity & nutrient profile.


Where to Find True Diagnostic & Hannah Went


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